AZOPA Feline & Canine Renal Support Twist-Off Capsules (60 Caps)
Live Probiotic & Prebiotic Complex for Enteric Dialysis and Azotemia Control
AZOPA is an ultra-premium veterinary supplement specifically formulated to manage azotemia in cats and dogs with IRIS stage 1-3 chronic kidney disease (CKD), while alleviating uremic toxication symptoms such as uremic gastritis, anorexia, vomiting, and halitosis. In cases of impaired renal filtration capacity, it acts through the intestinal flora to bind uremic toxins derived from protein fermentation within the intestinal lumen, safely eliminating them via feces. This mechanism, known as 'enteric dialysis', significantly relieves systemic toxic burden and enhances overall quality of life.
The formulation features a high concentration of multi-strain probiotics (including Bifidobacterium longum, Lactobacillus species, and Enterococcus strains) combined with prebiotic components such as psyllium husk, inulin, and FOS, working synergistically to restore microbiota balance. Manufactured in Zoopa's licensed GMP and ISO-compliant facilities, the proprietary Twist-Off capsule technology ensures active microorganisms are fully protected from moisture, light, and air. The capsule tip can be easily twisted open for direct administration or mixed into food.
Targeted Physiological Axes
The three essential physiological axes targeted and optimized at the cellular level by this formula
Renal & Uremic Load Control
Lightens renal filtration load and provides enteric dialysis by binding uremic toxins in the gut.
Gastrointestinal & Flora Support
Protects the digestive tract by reducing uremic gastritis, anorexia, and vomiting symptoms.
Systemic Detoxification
Enhances quality of life and appetite by supporting safe excretion of metabolic wastes.
Key Active Botanical & Bio-Actives
Pharmaceutical-grade bio-active constituents and their therapeutic roles
Bifidobacterium longum ve Probiyotik Kompleks
5 Milyar Canlı ProbiyotikProvides enteric dialysis by binding nitrogenous uremic toxins in the intestinal lumen, reducing renal workload.
Psyllium Husk & İnülin
150 mgAccelerates toxin excretion in the digestive tract with prebiotic fiber structure and nourishes microbiota.
FOS (Fruktooligosakkarit)
100 mgProtects intestinal barrier integrity by enhancing beneficial bacterial colonization.
Clinical & Biochemical Rationale
AZOPA operates on the axis of the gut-kidney axis, utilizing targeted probiotic strains and soluble dietary fibers to mitigate uremic syndrome in companion animals. In CKD, declining glomerular filtration rate (GFR) leads to the systemic accumulation of urea, creatinine, and indoxyl sulfate, which diffuse into the gut and exacerbate uremic enteritis. The synergistic action of Bifidobacterium longum, Lactobacillus species, and Enterococcus strains metabolizes nitrogenous waste products, converting them into microbial biomass rather than systemic toxins. Coupled with the mechanical binding properties of psyllium husk and inulin, AZOPA effectively executes enteric dialysis, significantly lowering blood urea nitrogen (BUN) levels and protecting the remaining nephron architecture from secondary inflammatory damage.
Veterinary Administration Standard
Recommended Dosage & Administration Protocol
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Recommended Dosage & Administration Protocol
- 01 Dosage is calculated based on body weight: For pets ≤ 5 kg: 1 capsule per day. For 5–10 kg: 2 capsules per day (1 morning, 1 evening). For ≥ 10 kg: 3 capsules per day (2 morning, 1 evening). The twist-off capsule tip is twisted open, and the content can be given directly into the mouth or mixed thoroughly with food, alongside adequate fresh drinking water.
Frequently Asked Questions
Essential clinical questions on formula kinetics, tolerance, and administration
What role does AZOPA play in the management of chronic kidney disease (CKD) in cats and dogs?
AZOPA aids in the management of uremic toxins in cats and dogs with chronic kidney disease (CKD), thereby alleviating disease symptoms. Its probiotic components (Bifidobacterium longum, Enterococcus thermophilus, Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus delbrueckii, Enterococcus faecium) and prebiotics (Psyllium husk, inulin, FOS) bind uremic toxins in the intestines and promote their excretion through feces, creating an enteric dialysis effect that contributes to lowering blood urea levels.
Which specific uremic toxins in animals with kidney failure are targeted by the probiotics and prebiotics in AZOPA?
The probiotics and prebiotics in AZOPA's formulation specifically target uremic toxins resulting from protein fermentation. These toxins include nitrogenous wastes such as urea, creatinine, indican, and phenolic compounds. By binding these substances within the intestinal lumen, their absorption is reduced, and their excretion via feces is facilitated, thereby lowering the amount of toxins entering systemic circulation.
How does AZOPA's 'enteric dialysis' mechanism improve symptoms of kidney failure?
AZOPA's 'enteric dialysis' mechanism utilizes the intestines as a filter to absorb uremic toxins from the bloodstream and facilitate their elimination through feces. This process helps alleviate CKD-related symptoms such as azotemia, uremic gastritis, anorexia, vomiting, and halitosis by reducing the toxin load when the kidneys are compromised.
How does the twist-off capsule formulation of AZOPA facilitate its administration in cats and dogs, and what are the dosage recommendations?
The twist-off capsule formulation of AZOPA allows for easy administration by dispensing the contents directly into the mouth or mixing it with food. The dosage is adjusted based on the animal's weight: 1 capsule daily for those up to 5 kg; 2 capsules daily (1 morning, 1 evening) for those between 5-10 kg; and 3 capsules daily (2 morning, 1 evening) for those over 10 kg. Ensuring adequate water intake during administration is important.
What are the effects of AZOPA on symptoms such as uremic gastritis and anorexia observed in cats and dogs?
AZOPA helps manage symptoms like uremic gastritis and anorexia in cats and dogs by reducing uremic toxins. The binding and elimination of toxins in the intestines decrease irritation in the AZOPA tract, improving the animal's overall comfort. This can contribute to the restoration of appetite and a reduction in symptoms like vomiting.
Where can you obtain Chosen Family formulas?
Our formulations are distributed exclusively through authorized veterinary hospitals and clinical practices to accompany veterinary care.
